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Symbol
Name
ID
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
MGI:104720
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations
Human Phenotypes
Abnormal urine sodium concentration
Renal sodium wasting
Nephrocalcinosis
Polyuria
Renal insufficiency
Disease(s) Associated with HSD11B2
apparent mineralocorticoid excess syndrome
type 1 diabetes mellitus

Mouse Phenotypes
enlarged kidney
decreased urine creatinine level
decreased urine potassium level
decreased urine sodium level
abnormal kidney morphology
dilated distal convoluted tubule
polyuria
Availability Mouse Genotype
Hsd11b2tm1Yko/Hsd11b2tm1Yko

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory